Wednesday, October 18, 2017

Ongoing Clinical Trials

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The gold standard for clinical interventions is the randomised controlled trial. This page provides a list of trials currently in progress trials.

1. TREATMENT OF IgA NEPHROPATHY WITH ANGIOTENSIN CONVERTING ENZYMES INHIBITORS (ACE-I): DESIGN OF A PROSPECTIVE RANDOMIZED MULTICENTER TRIAL Torino, Italy

2. THERAPEUTIC MULTICENTER TRIAL (STEROIDS ALONE VS STEROIDS PLUS AZATHIOPRINE) IN IgAN PATIENTS Lecco, Italy

3. ONE-YEAR ANGIOTENSIN-CONVERTING ENZYME INHIBITION PLUS MYCOPHENOLATE MOFETIL IMMUNOSUPPRESSION (AIM) IN THE COURSE OF EARLY IgA NEPHROPATHY: A MULTICENTRE, RANDOMISED, CONTROLLED, STUDY Pavia, Italy

4. A RANDOMIZED CONTROLLED TRIAL OF MYCOPHENOLATE MOFETIL (MMF) IN PATIENTS WITH IGA NEPHROPATHY Dallas, TX, USA

5. PROSPECTIVE RANDOMIZED CONTROLLED MULTICENTER TRIAL ON STEROIDS PLUS RAMIPRIL IN PROTEINURIC IGA NEPHROPATHY Bari, Italy

Many groups are interested in new trials to find out the best treatment for IgAN. We knew some of them only. If you are doing a prospective randomized control trial, please download, fill in the Clinical Trial Form, send it to the This email address is being protected from spambots. You need JavaScript enabled to view it. and we will be pleased to include your trial in this short list


1. TREATMENT OF IgA NEPHROPATHY WITH ANGIOTENSIN CONVERTING ENZYMES INHIBITORS (ACE-I): DESIGN OF A PROSPECTIVE RANDOMIZED MULTICENTER TRIAL

COORDINATOR Rosanna Coppo MD
Assistants: Licia Peruzzi, Sandro Amore, Monica Chiesa, Paola Cirina
FROM Nephrology, Dialysis and Transplantation Unit
Regina Margherita University Hospital
P Polonia 94,
CITY/ COUNTRY Torino, 10126, Italy
E-MAIL This email address is being protected from spambots. You need JavaScript enabled to view it.
FAX +39-011-6635543

REFERENCE Angiotensin-converting enzyme inhibitors (ACE-Is) in young patients with IgA nephropathy: effects against deterioration of renal function (European Biomed project EEC Concerted Action BMH4-97-2487 (OG 12-SSMI) Biomedicine and Health Research, (Nephrol Dial Transplant 1999;14:840-841) [PDF]

Acronym: IgACE

Clinical Trial Details

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2. THERAPEUTIC MULTICENTER TRIAL (STEROIDS ALONE VS STEROIDS PLUS AZATHIOPRINE) IN IgAN PATIENTS

COORDINATOR Claudio Pozzi (Francesco Locatelli, Claudio Ponticelli, Paolo Altieri)

FROM: FULL POSTAL ADDRESS
Nephrology and Dialysis Department, “A. Manzoni” Hospital, via dell’Eremo 9, 23900 Lecco
CITY/ COUNTRY Lecco/Italy
E-MAIL This email address is being protected from spambots. You need JavaScript enabled to view it.
FAX +39-0341-489860

Clinical Trial Details

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3. ONE-YEAR ANGIOTENSIN-CONVERTING ENZYME INHIBITION PLUS MYCOPHENOLATE MOFETIL IMMUNOSUPPRESSION (AIM) IN THE COURSE OF EARLY IgA NEPHROPATHY: A MULTICENTRE, RANDOMISED, CONTROLLED, STUDY.

COORDINATOR Prof. Antonio Dal Canton MD
FROM Nephrology, Dialysis and Transplantation
IRCCS Policlinico S. Matteo
P.le Golgi 2, 27100 Pavia, Italy
CITY/ COUNTRY Pavia / Italy
E-MAIL This email address is being protected from spambots. You need JavaScript enabled to view it.
FAX 0039 0382 52 6341
REFERENCE Research protol for the treatment of the IgA nephropathy


TEXT OF PROTOCOL
Title
One-year angiotensin-converting enzyme inhibition plus mycophenolate mofetil immunosuppression (AIM) in the course of early IgA nephropathy: A multicentre, randomised, controlled, study.

Acronym
The AIM IgAN study.

Study code
AIM 1

Clinical Trial Details

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4. A RANDOMIZED CONTROLLED TRIAL OF MYCOPHENOLATE MOFETIL (MMF) IN PATIENTS WITH IGA NEPHROPATHY

COORDINATOR Ronald J. Hogg, MD
Assistants: Dana Parrott, Shelley Long, Jeannette Lee, PhD
FROM SPNSG
Medical City Dallas Hospital
7777 Forest Lane Suite C-740
Dallas, Texas 75230
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

REFERENCE American Journal of Kidney Diseases 1995; 26: 792-6
Full Text Protocol
Website: www.spnsg.org

SPNSG Spring Newsletter

Acronym: MMF/IgAN Study

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5. PROSPECTIVE RANDOMIZED CONTROLLED MULTICENTER TRIAL ON STEROIDS PLUS RAMIPRIL IN PROTEINURIC IGA NEPHROPATHY

COORDINATOR C. Manno
Assistants: Gesualdo L, D'Altri C, Rossini M, Grandaliano G, Schena FP
FROM Department of Emergency and Organs Transplantation, University of Bari, Italy
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

REFERENCE Prospective randomized controlled multicenter trial on steroids plus ramipril in proteinuric IgA nephropathy.
J Nephrol 2001 Jul-Aug;14(4):248-52
Full Text Protocol

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